NCT00147914

Comparison Study Between Cefdinir & Amoxicilline/Clavulanate in Acute Sinusitis and Assessment of Quality of Life

A Comparison Study Between Cefdinir and Amoxicilline/Clavulanate in Patients With Acute Sinusitis and Assessment of Quality of Life (QOL)

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: University of Chicago · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study is a comparison between two commonly used antibiotics (Cefdinir vs. Amoxicillin/Clavulanate) in patients with acute sinus infection, surveying quality of life. The hypothesis is that the two treatments would be at the least equivalent based on clinical outcome measures of improvement in quality of life.

Detailed description

The purpose if this investigation is to evaluate the rate of improvement ub Quality of LIfe (QOL) in two different medications, a 10-day course of Cefdinir 300 mg PO BID versus a 10-day course of Amoxicillin/Clavulanate 1000 mg/62.5 mg XR BID, in the treatment of acute bacterial sinusitis.

Conditions

• Acute Bacterial Sinusitis

Interventions

Type	Name	Description
DRUG	Cefdinir (drug)	cefdinir 300mg per orally twice daily for 10 days
DRUG	amoxicillin/clavulanate	1000mg /62.5mg extended release per orally twice daily for 10 days

Timeline

• Start date: 2005-02-01
• Primary completion: 2007-02-01
• Completion: 2017-02-18
• First posted: 2005-09-07
• Last updated: 2017-05-02

Locations

1 site across 1 country: United States