Trials / Completed
CompletedNCT00147875
Study of Prednisone, Vinblastine, Doxorubicin, and Gemcitabine in Elderly Patients With Advanced Stages Hodgkin's Lymphoma
PVAG - Phase I/II Dose Finding Trial in Elderly Patients (> 60 Years) With Advanced Stages Hodgkin's Lymphoma
- Status
- Completed
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 60 (actual)
- Sponsor
- University of Cologne · Academic / Other
- Sex
- All
- Age
- 60 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The objectives of this study are to assess the feasibility and efficacy of a combination chemotherapy (PVAG) in elderly patients with advanced stages Hodgkin's lymphoma.
Detailed description
Gemcitabine shows promising activity in patients with relapsed lymphoma either administered as single agent or in combination with other cytotoxic agents. No trial to date evaluated its role in patients with primary Hodgkin's lymphoma. We therefore developed a three-weekly regimen based on the standard ABVD regimen.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Prednisone | |
| DRUG | Vinblastine | |
| DRUG | Doxorubicin (Adriamycin) | |
| DRUG | Gemcitabine |
Timeline
- Start date
- 2004-03-01
- Primary completion
- 2007-07-01
- First posted
- 2005-09-07
- Last updated
- 2009-09-07
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT00147875. Inclusion in this directory is not an endorsement.