NCT00145262

TACT-NAGOYA: Therapeutic Angiogenesis Using Cell Transplantation

Therapeutic Angiogenesis Using Cell Transplantation (TACT) Study at Nagoya

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: —
• Sponsor: Nagoya University · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Clinical studies have established that implantation of bone marrow mononuclear cells (BM-MNCs) or peripheral blood mononuclear cells (PB-MNCs) into ischaemic limbs increases collateral vessel formation. We, the investigators at Nagoya University, further investigated the efficacy and safety of autologous implantation of BM-MNCs or PB-MNCs in patients with severe ischaemic limbs who have no other alternative therapeutic options. We also examined a potential limiting factor which reduced the efficacy of therapeutic angiogenesis using cell transplantation (TACT).

Conditions

• Buerger Disease
• Arteriosclerosis Obliterans

Interventions

Type	Name	Description
PROCEDURE	Autologous Bone Marrow Mononuclear Cell Implantation

Timeline

• Start date: 2003-08-01
• First posted: 2005-09-05
• Last updated: 2005-12-30

Locations

1 site across 1 country: Japan