Trials / Completed
CompletedNCT00144729
Conditioning Regimens for Patients With Severe Aplastic Anemia Transplanted With Marrow From an Unrelated Donor
- Status
- Completed
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 85 (planned)
- Sponsor
- Fred Hutchinson Cancer Center · Academic / Other
- Sex
- All
- Age
- 55 Years
- Healthy volunteers
- Not accepted
Summary
A single arm dose optimization study in which all patients are given a fixed dose of Cytoxan (4 x 50 mg/kg) plus ATG (3 x 30 mg/kg) and the TBI dose starting at 3 x 200 cGy is escalated or de-escalated dependent upon engraftment and toxicity.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Bone marrow transplant |
Timeline
- Start date
- 1993-05-01
- Completion
- 2007-07-01
- First posted
- 2005-09-05
- Last updated
- 2008-04-30
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00144729. Inclusion in this directory is not an endorsement.