Trials / Unknown
UnknownNCT00142324
CALM-AD
A Randomised Placebo Controlled Trial of a Cholinesterase Inhibitor in the Management of Agitation in Dementia That is Unresponsive to a Psychological Intervention
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 190 (planned)
- Sponsor
- Institute of Psychiatry, London · Academic / Other
- Sex
- All
- Age
- 40 Years
- Healthy volunteers
- Accepted
Summary
Primary Aim To determine whether; * Donepezil is significantly better than placebo in the management of agitation in Alzheimer's Disease that has not responded to, or is inappropriate for a standardised brief psychosocial treatment Secondary Aims To determine whether; * Donepezil has a significant positive or negative impact upon quality of life compared with placebo * whether there is a significant difference between Donepezil and placebo with respect to cognitive performance * the cost effectiveness of the pharmacological treatment for agitation
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Donepezil |
Timeline
- Start date
- 2003-11-01
- Completion
- 2005-12-01
- First posted
- 2005-09-02
- Last updated
- 2005-12-14
Locations
8 sites across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT00142324. Inclusion in this directory is not an endorsement.