Trials / Terminated
TerminatedNCT00141583
The Renin-Angiotensin System in Essential Hypertension
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 11 (estimated)
- Sponsor
- St George's, University of London · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
Although ACE Inhibitors and Angiotensin Receptor Blockers are effective blood pressure lowering agents, the exact mechanisms by which these agents lower BP are still not fully understood. This study aims to compare the blood pressure and hormonal responses (plasma renin activity and aldosterone) to the ACE inhibitor enalapril and ARB candesartan in individuals with mild essential hypertension.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Enalapril 20 mg bd | |
| DRUG | Candesartan 8 mg bd |
Timeline
- Start date
- 2004-04-01
- Completion
- 2006-10-01
- First posted
- 2005-09-01
- Last updated
- 2015-06-09
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT00141583. Inclusion in this directory is not an endorsement.