Clinical Trials Directory

Trials / Completed

CompletedNCT00140374

Vaccination Priming and Vaccine Boosting Trial of Allogeneic Human GM-CSF Gene Transduced Irradiated Prostate Cancer Cell Vaccines (GVAX® Vaccine for Prostate Cancer)

Phase I/II Study of Vaccination Priming and Vaccine Boosting With Allogeneic Human GM-CSF Gene Transduced Irradiated Prostate Cancer Cell Vaccines in Patients With Prostate Cancer

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
36 (planned)
Sponsor
Cell Genesys · Industry
Sex
Male
Age
18 Years
Healthy volunteers
Not accepted

Summary

The objective of this study is to evaluate the safety and efficacy of priming vaccinations, and subsequent boosting vaccinations with GVAX® Vaccine for Prostate Cancer. Clinical observations and laboratory measurements will be monitored to evaluate safety and toxicity. Additionally, the antitumor effects of GVAX® Vaccine for Prostate Cancer on serum PSA levels, will be evaluated and antitumor responses will be quantitated.

Conditions

Interventions

TypeNameDescription
BIOLOGICALImmunotherapy allogeneic GM-CSF secreting cellular vaccine

Timeline

Start date
1998-12-01
Completion
2001-02-01
First posted
2005-09-01
Last updated
2005-09-01

Source: ClinicalTrials.gov record NCT00140374. Inclusion in this directory is not an endorsement.