Clinical Trials Directory

Trials / Completed

CompletedNCT00136513

SB-743921 In Patients With Solid Tumors

A Phase I Study to Determine the Safety and Pharmacokinetics of Intravenous Administration of SB743921 on a Once Every 3 Week Schedule in Patients With Solid Tumors

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
30 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to find a dose of SB-743921 in adult patients with solid tumors or lymphoma who have progressed on standard therapy or who have relapsed. SB-743921 is dosed by 1-hour intravenous infusion every 3 weeks. A patient may continue to receive treatment as long as they are benefiting from the treatment. Blood samples will be taken at specific times to measure the amount of the drug in your body at specific times after the drug is given. Blood samples will also be taken for lab tests such as complete blood counts and clinical chemistries. Physical exams will be performed before each treatment with SB-743921. During the treatment phase, the patients will undergo regular assessments for safety and clinical response.

Conditions

Interventions

TypeNameDescription
DRUGSB-743921

Timeline

Start date
2004-04-01
First posted
2005-08-29
Last updated
2008-10-16

Locations

2 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00136513. Inclusion in this directory is not an endorsement.