NCT00132184

Vitamin D Treatment for Crohn´s Disease

Remission Keeping and Remission Inducing Effect by Vitamin-D in Crohns Disease, and in Vitro Vitamin-D Mediated T-Cell Immunomodulation

• Status: Unknown
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 110 (planned)
• Sponsor: University of Aarhus · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to examine whether vitamin D treatment is effective in Crohn's disease.

Detailed description

Crohns Disease is an inflammatory disease of primarily the small intestine and colon. In recent years scientists have hypothesized that low blood vitamin-D levels play a role in the development of autoimmune diseases, including Crohns disease. The purpose of this study is to examine whether vitamin-D is effective in keeping remission in inactive Crohns Disease (double blind placebo controlled trial). The patients who have active disease in the placebo group (reach primary endpoint), will in an open setting receive a higher single dose vitamin-D and the effect will be measured within 4 weeks.

Conditions

• Crohns Disease

Interventions

Type	Name	Description
DRUG	Vitamin D

Timeline

• Start date: 2005-09-01
• Completion: 2008-02-01
• First posted: 2005-08-19
• Last updated: 2007-04-13

Locations

4 sites across 1 country: Denmark