Clinical Trials Directory

Trials / Completed

CompletedNCT00131677

Extended Safety Study of Tenofovir Disoproxil Fumarate (TDF) Among HIV-1 Negative Men

Phase II Extended Safety Study of Tenofovir Disoproxil Fumarate (TDF) Among HIV-1 Negative Men

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
400 (actual)
Sponsor
Centers for Disease Control and Prevention · Federal
Sex
Male
Age
18 Years – 60 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to examine safety and tolerability of daily tenofovir use in HIV-uninfected men.

Detailed description

This study will assess the clinical and behavioral safety and tolerability of oral daily TDF use as pre-exposure prophylaxis (PrEP) to prevent HIV infection in uninfected men.

Conditions

Interventions

TypeNameDescription
DRUGtenofovir disoproxil fumaratestudy product taken daily
DRUGplacebostudy product taken daily

Timeline

Start date
2005-02-01
Primary completion
2009-08-01
Completion
2009-08-01
First posted
2005-08-19
Last updated
2014-03-10
Results posted
2014-03-10

Locations

3 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00131677. Inclusion in this directory is not an endorsement.