NCT00130572

Efficacy of Elidel Cream on Erosive Oral Lichen Planus

Randomized Placebo-Controlled Clinical Pilot Trial Regarding the Efficacy of Elidel Cream on Erosive Oral Lichen Planus

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: University Hospital Tuebingen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate whether topical applied pimecrolimus will lead to improvement of erosive oral lichen planus. This effect will be monitored by reduction of erosive mucosal area and reduction of patient's pain symptoms.

Detailed description

Oral lichen planus is a mucosal inflammatory disease of unknown origin. It can be very painful especially if erosions appear on the oral mucosa. In this study the efficacy of pimecrolimus compared to placebo in treatment of erosive oral lichen planus will be investigated. To this end the subjective pain and the amount of affected mucosa will be monitored before and after treatment.

Conditions

• Lichen Planus, Oral

Interventions

Type	Name	Description
DRUG	Pimecrolimus

Timeline

• Start date: 2004-06-01
• Primary completion: 2007-12-01
• Completion: 2007-12-01
• First posted: 2005-08-15
• Last updated: 2008-05-23

Locations

1 site across 1 country: Germany