Trials / Completed

CompletedNCT00129207

Ketoconazole Administration: How it is Affected by the Body and Broken Down and How it Acts on the Body When Used With Velcade

Effect of Ketoconazole Administration on the Pharmacokinetics and Pharmacodynamics of Bortezomib in Patients With Advanced Solid Tumors

Status: Completed
Phase: Phase 1
Study type: Interventional
Enrollment: —

Sponsor: Millennium Pharmaceuticals, Inc. · Industry
Sex: All
Age: 18 Years
Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate how ketoconazole (Nizoral) affects the pharmacokinetics (how the study drug is affected by the body and broken down) and pharmacodynamics (how the study drug acts on the body) of the active ingredient in the study drug Velcade (bortezomib).

Conditions

Tumors

Interventions

Type	Name	Description
DRUG	bortezomib

Timeline

Primary completion: 2006-09-01
First posted: 2005-08-11
Last updated: 2008-02-11

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00129207. Inclusion in this directory is not an endorsement.