Clinical Trials Directory

Trials / Completed

CompletedNCT00127127

A Study of Vorinostat in Patients With Solid Tumors (MK-0683-029)

A Phase I Clinical Study of L-001079038 in Patients With Solid Tumors

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
18 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
All
Age
20 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The primary purpose of this trial is to determine the maximum tolerated dose (MTD), or the maximum acceptable dose (MAD) and evaluate the dose limiting toxicity (DLT) of oral suberoylanilide hydroxamic acid in participants with solid tumors.

Conditions

Interventions

TypeNameDescription
DRUGvorinostatvorinostat 100 mg, 200 mg, 400 mg, or 500 mg single oral dose; once-daily or twice-daily administration

Timeline

Start date
2005-06-10
Primary completion
2009-08-21
Completion
2009-08-21
First posted
2005-08-05
Last updated
2022-09-13
Results posted
2022-05-02

Source: ClinicalTrials.gov record NCT00127127. Inclusion in this directory is not an endorsement.

A Study of Vorinostat in Patients With Solid Tumors (MK-0683-029) (NCT00127127) · Clinical Trials Directory