Clinical Trials Directory

Trials / Completed

CompletedNCT00126945

Evaluate 4 Different Formulations of Meningococcal Serogroups A,C,W-135,Y Conjugate Vaccine When Given as 1 Dose to Healthy Subjects Aged 15-19 Yrs

A Primary Vaccination Study to Assess the Immunogenicity, Safety & Reactogenicity of 1 Dose of 4 Different Formulations of GSK Biologicals' Meningococcal Conjugate Vaccine (MenACWY) vs 1 Dose of MENCEVAX™ ACWY in Healthy Subjects Aged 15-19 Years

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
125 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
15 Years – 19 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to evaluate the immunogenicity, safety and reactogenicity of one dose of four different formulations of the MenACWY conjugate vaccine when given to healthy subjects aged 15-19 years. The selection of the best formulation will be based on data obtained up to one month after the vaccine dose.

Detailed description

The study is open. However, the 4 different formulations of GSK's MenACWY conjugate vaccine will be administered in a double-blind manner. Mencevax™ ACWY vaccine will serve as active control. Subjects will receive one vaccine dose only (GSK's MenACWY conjugate vaccine or Mencevax™ ACWY vaccine), and will have 2 blood samples taken, before and one month after vaccination.

Conditions

Interventions

TypeNameDescription
BIOLOGICALMeningococcal Vaccine

Timeline

Start date
2005-08-01
Completion
2005-10-01
First posted
2005-08-05
Last updated
2016-09-21

Locations

1 site across 1 country: Denmark

Source: ClinicalTrials.gov record NCT00126945. Inclusion in this directory is not an endorsement.