NCT00124995

Trial of Terbutaline for the Treatment of Status Asthmaticus in Children

Double-blinded Randomized Trial of Terbutaline to Shorten ICU Length of Stay in the Treatment of Status Asthmaticus in Children

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 40 (planned)
• Sponsor: Connecticut Children's Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

Although widely used for the treatment of pediatric status asthmaticus, intravenous terbutaline has potentially significant side effects; may not improve outcomes; and may increase Intensive Care Unit (ICU) length of stay. This study is designed to test the efficacy of intravenous terbutaline for the treatment of status asthmaticus by adding intravenous terbutaline or placebo to standard asthma treatment. The dose of terbutaline or placebo will be titrated according to severity of illness as quantified by a validated clinical asthma score. Differences in outcomes between the study groups, such as length of stay, hospital costs, and lung function will be compared.

Conditions

• Status Asthmaticus

Interventions

Type	Name	Description
DRUG	terbutaline

Timeline

• Start date: 2003-10-01
• Primary completion: 2006-10-01
• Completion: 2006-10-01
• First posted: 2005-07-29
• Last updated: 2013-02-15

Locations

1 site across 1 country: United States