Trials / Completed
CompletedNCT00124540
Misoprostol for Preventing Postpartum Hemorrhage
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 1,200 (actual)
- Sponsor
- Gynuity Health Projects · Academic / Other
- Sex
- Female
- Age
- —
- Healthy volunteers
- Accepted
Summary
This hospital-based, multicenter, randomized, placebo-controlled trial will assess the effects of misoprostol as part of active management of the third stage of labor on postpartum blood loss, complications, and side effects. Twelve hundred eligible women will receive routine oxytocics (oxytocin 5-10 IU) plus either 400 mcg sublingual misoprostol or placebo during or immediately after delivery. The primary outcome will be measured blood loss of =\>500 mls within one hour after enrollment.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | misoprostol | |
| DRUG | placebo | placebo resembling misoprosotl |
Timeline
- Start date
- 2005-08-01
- Primary completion
- 2007-09-01
- Completion
- 2007-10-01
- First posted
- 2005-07-28
- Last updated
- 2008-05-28
Locations
5 sites across 3 countries: Nigeria, South Africa, Uganda
Source: ClinicalTrials.gov record NCT00124540. Inclusion in this directory is not an endorsement.