Clinical Trials Directory

Trials / Completed

CompletedNCT00124215

Safety and Efficacy of the Therapeutic Vaccine GI-5005 Versus Placebo for the Treatment of Chronic Hepatitis C Infection

A Phase 1 Double-Blind, Placebo Controlled, Dose-Escalation, Multi-center Therapeutic Trial of the Safety, Immunogenicity, and Efficacy of GI-5005; an Inactivated Recombinant Saccharomyces Cerevisiae Expressing a Hepatitis C Virus NS3-Core Fusion Protein, in Patients With Chronic Hepatitis C Infection

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
48 (estimated)
Sponsor
GlobeImmune · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The GI-5005 therapeutic vaccine or placebo will be injected under the skin of hepatitis C virus (HCV) subjects. Patients will be monitored for safety, immune responses and any therapeutic benefits related to the injections.

Conditions

Interventions

TypeNameDescription
BIOLOGICALGI-5005Heat-killed yeast cell transfected with NS3-Core fusion protien.

Timeline

Start date
2005-06-01
Primary completion
2007-06-01
Completion
2010-02-01
First posted
2005-07-27
Last updated
2010-05-05

Locations

5 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00124215. Inclusion in this directory is not an endorsement.