NCT00123214

A Change in Diet May Decrease the Negative Consequences of Chronic Sleep Deprivation

Pilot Study: A Dietary Intervention May Decrease the Negative Metabolic and Cognitive Consequences of Chronic Sleep Deprivation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (planned)
• Sponsor: St. Vincent's Medical Center · Unknown
• Sex: All
• Age: 25 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine whether or not a low calorie, low glycemic index diet with omega-3 fatty acid supplements can prevent some of the negative consequences of sleep deprivation.

Detailed description

This pilot study included 18 medical residents at two academic medical centers in New York City. All residents who participated in the study were assigned to work a night shift schedule for two weeks, and began the study on the morning prior to their first evening shift. The study subjects were randomly assigned to one of two groups: * Intervention diet -- consisting of 40% carbohydrates, 30% protein, and 30% fat with 2.4g of long chain fatty acid supplements (n=9) Total calories for males was 1600/day, and 1200/day for females * Control group -- ad lib diet. Main outcome measures included: * weight * resting metabolic rate * percent body fat * lipid profile * CRP * fasting glucose and insulin levels * urinary neurotransmitter levels * salivary cortisol * six cognitive tests of memory, attention, and executive function. Subjects were tested on day 1, 7, and 14 of the study.

Conditions

• Sleep Deprivation

Interventions

Type	Name	Description
DRUG	Controlled Dietary Intervention

Timeline

• Start date: 2004-09-01
• Completion: 2005-04-01
• First posted: 2005-07-22
• Last updated: 2006-06-27

Locations

1 site across 1 country: United States