Clinical Trials Directory

Trials / Completed

CompletedNCT00122317

Extension Study of Eculizumab in Patients With Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH)

Open Label Extension Study of Eculizumab in Patients With Transfusion Dependent PNH

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
187 (actual)
Sponsor
Alexion Pharmaceuticals, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the long-term safety of eculizumab in patients with transfusion dependent hemolytic PNH.

Detailed description

An open-label extension study to evaluate long-term safety of eculizumab in PNH patients who had completed the TRIUMPH (C04-001), SHEPHERD (C04-002), and X03-001 studies.

Conditions

Interventions

TypeNameDescription
DRUGeculizumab

Timeline

Start date
2005-05-01
Primary completion
2008-09-01
Completion
2008-10-01
First posted
2005-07-22
Last updated
2018-03-13
Results posted
2017-06-05

Locations

40 sites across 12 countries: United States, Australia, Belgium, Canada, France, Germany, Ireland, Italy, Netherlands, Spain, Sweden, United Kingdom

Source: ClinicalTrials.gov record NCT00122317. Inclusion in this directory is not an endorsement.