Trials / Unknown
UnknownNCT00116311
Effects of Allergen Inhalation on Adenosine Receptor Expression in Sputum and Peripheral Blood
Effects of Allergen Inhalation on Adenosine Receptor Expression and Mast Cell Activation in Peripheral Blood and Sputum of Asthmatics and Healthy Subjects
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 20 (planned)
- Sponsor
- Groningen Research Institute for Asthma and COPD · Academic / Other
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to determine whether asthmatics have different adenosine receptor expression profiles than healthy controls. We hypothesize that asthmatics will have increased adenosine receptor expression versus control subjects. We also want to study the effects of allergen inhalation on adenosine receptor expression in asthmatics. We believe that adenosine receptor expression will be upregulated after allergen inhalation. Both hypotheses are being tested in sputum and peripheral blood.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | allergen inhalation | |
| BEHAVIORAL | withdrawal of medication | |
| PROCEDURE | sputum induction |
Timeline
- Start date
- 2005-07-01
- Completion
- 2007-02-01
- First posted
- 2005-06-29
- Last updated
- 2007-03-21
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT00116311. Inclusion in this directory is not an endorsement.