Clinical Trials Directory

Trials / Completed

CompletedNCT00107016

Everolimus and Letrozole as Preoperative Therapy of Primary Breast Cancer in Post-menopausal Women

A Phase 2, Double-blind, Randomized, Placebo-controlled, Multi-center Study Assessing the Value of Adding Everolimus to Letrozole as Preoperative Therapy of Primary Breast Cancer in Postmenopausal Women

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
267 (actual)
Sponsor
Novartis Pharmaceuticals · Industry
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to examine the effect of the combination of everolimus and letrozole compared to placebo and letrozole as pre-surgical therapy in patients with newly diagnosed estrogen receptor positive breast cancer.

Conditions

Interventions

TypeNameDescription
DRUGRAD001, Letrozole 2.5mg
DRUGLetrozole 2.5mg

Timeline

Start date
2005-03-01
Primary completion
2007-04-01
Completion
2007-04-01
First posted
2005-04-05
Last updated
2013-03-04

Locations

46 sites across 10 countries: United States, Austria, Belgium, Canada, France, Germany, Italy, Russia, Spain, United Kingdom

Source: ClinicalTrials.gov record NCT00107016. Inclusion in this directory is not an endorsement.

Everolimus and Letrozole as Preoperative Therapy of Primary Breast Cancer in Post-menopausal Women (NCT00107016) · Clinical Trials Directory