Clinical Trials Directory

Trials / Completed

CompletedNCT00105300

Study of the Human Anti-TNF Monoclonal Antibody Adalimumab for the Induction of Clinical Remission in Subjects With Crohn's Disease

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Human Anti-TNF Monoclonal Antibody Adalimumab for the Induction of Clinical Remission in Subjects With Moderate to Severe Crohn's Disease Who Have Lost Response or Are Intolerant to Infliximab

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
300 (planned)
Sponsor
Abbott · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The goal of this study is to test whether adalimumab can induce clinical remission in subjects with active Crohn's disease who have been initially treated with infliximab and either lost response or discontinued its use as a result of intolerance to the drug.

Conditions

Interventions

TypeNameDescription
DRUGAdalimumab

Timeline

Start date
2004-10-01
First posted
2005-03-14
Last updated
2006-08-15

Locations

56 sites across 4 countries: United States, Belgium, Canada, France

Source: ClinicalTrials.gov record NCT00105300. Inclusion in this directory is not an endorsement.

Study of the Human Anti-TNF Monoclonal Antibody Adalimumab for the Induction of Clinical Remission in Subjects With Croh (NCT00105300) · Clinical Trials Directory