Clinical Trials Directory

Trials / Completed

CompletedNCT00104065

Safety and Efficacy of CG53135-05 in the Prevention of Oral Mucositis in Patients Receiving Bone Marrow Transplant

A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of the Safety and Efficacy of CG53135-05 Administered Intravenously as a Single Dose for the Prevention of Oral Mucositis in Patients Receiving Autologous Hematopoietic Stem Cell Transplant

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
Sponsor
CuraGen Corporation · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

CG53135-05, a recombinant human fibroblast growth factor-20 (rhFGF-20) protein, is under investigation for the prevention of oral mucositis. Oral mucositis is a commonly occurring side effect of high-dose chemotherapy in patients undergoing autologous hematopoietic stem cell transplant. The objective of this Phase II trial is to evaluate the safety and efficacy of CG53135-05 when administered as a single dose to patients at risk for developing oral mucositis.

Conditions

Interventions

TypeNameDescription
DRUGCG53135-05, velafermin

Timeline

Start date
2005-01-01
Primary completion
2005-12-01
Completion
2005-12-01
First posted
2005-02-23
Last updated
2016-03-15

Locations

9 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00104065. Inclusion in this directory is not an endorsement.

Safety and Efficacy of CG53135-05 in the Prevention of Oral Mucositis in Patients Receiving Bone Marrow Transplant (NCT00104065) · Clinical Trials Directory