Clinical Trials Directory

Trials / Terminated

TerminatedNCT00100737

Comparing Interleukin-2 (IL-2) Combined With Rituximab (Rituxan) to Rituximab Alone in Subjects With Non-Hodgkin's Lymphoma (NHL)

A Phase 2 Randomized, Open-Label, Controlled Trial of the Addition of 8 Weeks SC Administration of Aldesleukin (Rh-Interleukin-2 [IL-2]) to 4 Weeks of IV Administration of Rituximab in the Treatment of Rituximab Naïve Subjects With Follicular Non-Hodgkin's Lymphoma, Refractory or Relapsed After Previous Chemotherapy

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
300 (planned)
Sponsor
Chiron Corporation · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine whether interleukin-2 given 3 times weekly for 8 weeks in combination with rituximab is effective and safe when compared to rituximab given alone in the treatment of follicular NHL subjects that have never received rituximab as a treatment and are refractory or relapsed after previous chemotherapy.

Conditions

Interventions

TypeNameDescription
DRUGinterleukin-2
DRUGrituximab

Timeline

First posted
2005-01-07
Last updated
2006-02-06

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00100737. Inclusion in this directory is not an endorsement.