NCT00097916

An Evaluation of the Safety and Efficacy of Memantine in Agitated Patients With Moderate to Severe Alzheimer's Disease

A Randomized, Double-Blind, Placebo-Controlled Evaluation of the Safety and Efficacy of Memantine in Non-Institutionalized Agitated Patients With Moderate to Severe Alzheimer's Disease

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 34 (actual)
• Sponsor: Forest Laboratories · Industry
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

About 65% of patients with severe Alzheimer's Disease (AD) will have symptoms of agitation. There are drawbacks associated with the currently available therapeutic interventions for agitation associated with Alzheimer's Disease. In a recent trial, in the group of patients with moderate to severe AD treated with memantine, there were fewer incidences of agitation. It is hypothesized that memantine will be effective in reducing the symptoms of agitation associated with moderate to severe Alzheimer's Disease.

Conditions

• Alzheimer's Disease

Interventions

Type	Name	Description
DRUG	memantine HCl

Timeline

• Start date: 2004-09-01
• Primary completion: 2006-04-01
• Completion: 2006-04-01
• First posted: 2004-12-02
• Last updated: 2012-03-05

Locations

9 sites across 1 country: United States