NCT00093054

Cranberry Juice for Treatment of Urinary Tract Infections

Cranberry Juice and Urinary Tract Infections

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 319 (actual)
• Sponsor: National Center for Complementary and Integrative Health (NCCIH) · NIH
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether daily consumption of cranberry juice lessens the symptoms and prevents the recurrence of urinary tract infections (UTIs). This study will also determine whether drinking cranberry juice for 6 months selects for less virulent bacteria in the rectal, vaginal, and urethral areas.

Detailed description

Participants in this study will be randomly assigned to consume either 8 ounces of cranberry juice or placebo juice twice a day for 6 months. Participants will have follow-up visits at 3 and 6 months, and whenever they experience a symptomatic episode. Urine, vaginal and rectal specimens will be taken at each visit to test for the presence of bacteria that cause urinary tract infections. Participants will complete a questionnaire at study entry, Day 3, Weeks 1 and 2, and monthly thereafter or whenever there is a recurrence of symptoms.

Conditions

• Urinary Tract Infections

Interventions

Type	Name	Description
DRUG	Cranberry juice	TID dosage for UTI treatment
DIETARY_SUPPLEMENT	Placebo cranberry juice	TID placebo dosage to match active comparator

Timeline

• Start date: 2004-11-01
• Primary completion: 2008-03-01
• Completion: 2009-12-01
• First posted: 2004-10-01
• Last updated: 2015-05-05

Locations

1 site across 1 country: United States