Clinical Trials Directory

Trials / Completed

CompletedNCT00087763

Pegaptanib Sodium on Foveal Thickening in Patients With Exudative Subfoveal Age-Related Macular Degeneration (AMD)

A Phase II Prospective, Randomized, Double-Masked, Sham-Controlled, Dose-Ranging, Multi-Center Trial to Assess the Effect of Pegaptanib Sodium on Foveal Thickening in Patients With Exudative Subfoveal Age-Related Macular Degeneration (AMD)

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
135 (planned)
Sponsor
Eyetech Pharmaceuticals · Industry
Sex
All
Age
50 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine if Macugen™ reduces foveal thickness and improves vision in patients with wet AMD.

Detailed description

This will be a randomized, double-masked, controlled, dose-ranging, multi-center comparative trial, in parallel groups. Patients will be stratified by clinical center and foveal thickness to be treated either Macugen or a sham injection. After 24 weeks, all patients will treated with Macugen until the end of the study at 54 weeks.

Conditions

Interventions

TypeNameDescription
DRUGMacugen ™ (pegaptanib sodium injection)

Timeline

Start date
2004-03-01
Completion
2006-05-01
First posted
2004-07-16
Last updated
2006-05-03

Source: ClinicalTrials.gov record NCT00087763. Inclusion in this directory is not an endorsement.