Clinical Trials Directory

Trials / Terminated

TerminatedNCT00086346

Study Evaluating of Calcineurin Inhibitor and Sirolimus (Rapamune) Treatment in Liver Transplant Recipients

A Randomized, Open-Label, Comparative Evaluation of Conversion From Calcineurin Inhibitor Treatment to Sirolimus Treatment Versus Continued Calcineurin Inhibitor Treatment in Liver Allograft Recipients Undergoing Maintenance Therapy

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
607 (actual)
Sponsor
Wyeth is now a wholly owned subsidiary of Pfizer · Industry
Sex
All
Age
13 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the sirolimus conversion regimen as compared with the calcineurin inhibitor continuation regimen with regards to renal function in stable liver transplant subjects.

Conditions

Interventions

TypeNameDescription
DRUGSirolimus (Rapamune)
DRUGCyclosporine or Tacrolimus

Timeline

Start date
2002-12-01
Primary completion
2008-07-01
Completion
2008-07-01
First posted
2004-07-02
Last updated
2010-04-28
Results posted
2009-09-07

Locations

42 sites across 12 countries: United States, Belgium, Canada, Czechia, France, Germany, Italy, Netherlands, Portugal, Spain, Switzerland, United Kingdom

Source: ClinicalTrials.gov record NCT00086346. Inclusion in this directory is not an endorsement.

Study Evaluating of Calcineurin Inhibitor and Sirolimus (Rapamune) Treatment in Liver Transplant Recipients (NCT00086346) · Clinical Trials Directory