Clinical Trials Directory

Trials / Terminated

TerminatedNCT00086164

Prevention of Vascular Access Graft Failure in Patients With Chronic Renal Failure Requiring Hemodialysis

A Phase 1/2, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Pilot Trial to Assess the Effect of Treatment of the Recipient Vein of a Polytetrafluoroethylene (PTFE) Vascular Access Graft With Two Concentrations of E2F Decoy as Compared to Placebo on Neointimal Hyperplasia and the Preservation of Graft Function in Patients With Chronic Renal Failure Requiring Hemodialysis

Status
Terminated
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
Sponsor
Anesiva, Inc. · Industry
Sex
All
Age
18 Years – 79 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the effect of recipient vein pretreatment of edifoligide (E2F Decoy), compared to placebo, on graft/recipient vein stenosis in polytetrafluoroethylene (PTFE) vascular access grafts placed for hemodialysis at 6 months after enrollment.

Conditions

Interventions

TypeNameDescription
DRUGedifoligide (E2F Decoy)

Timeline

Start date
2004-05-01
First posted
2004-06-29
Last updated
2005-07-19

Locations

21 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00086164. Inclusion in this directory is not an endorsement.

Prevention of Vascular Access Graft Failure in Patients With Chronic Renal Failure Requiring Hemodialysis (NCT00086164) · Clinical Trials Directory