NCT00079963

Gender, Obesity, C-Reactive Protein, and Oxidative Stress

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 396 (actual)
• Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · NIH
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This randomized placebo-controlled trial will test whether supplementing with vitamins C and E can lower markers of inflammation and oxidative stress in healthy adults. We will examine whether one antioxidant vitamin is more effective than another, and whether gender or body fat influence the treatment effects. We will also determine whether gender, body fat, or menopausal status are associated with baseline concentrations of inflammation and oxidative stress markers.

Detailed description

Participants will be given 1000 mg vitamin C or 800 IU vitamin E daily for 60 days.

Conditions

• Cardiovascular Disease

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Vitamin C	1000 mg/day
DIETARY_SUPPLEMENT	Vitamin E	800 IU/day
DIETARY_SUPPLEMENT	Placebo

Timeline

• Start date: 2004-04-01
• Primary completion: 2008-03-24
• Completion: 2008-03-24
• First posted: 2004-03-22
• Last updated: 2017-09-27

Locations

1 site across 1 country: United States