Trials / Completed
CompletedNCT00065741
Botanical/Drug Interactions in HIV: Glucuronidation
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 60 (planned)
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH) · NIH
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
A series of clinical studies will be conducted in normal, healthy adult volunteers to evaluate the potential for alterations in the pharmacokinetics of anti HIV drugs when botanicals/nutriceuticals are given concurrently via the oral route. Both the drugs and botanicals are known to rely upon or to modulate, respectively, metabolism via glucuronidation.
Detailed description
As per Brief Summary
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | silymarin |
Timeline
- Start date
- 2003-09-01
- Completion
- 2006-03-01
- First posted
- 2003-08-01
- Last updated
- 2007-03-23
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00065741. Inclusion in this directory is not an endorsement.