NCT00062452

Esophageal Motility and Airway Defenses Among Infants

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 65 (actual)
• Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · NIH
• Sex: All
• Age: 2 Weeks – 6 Months
• Healthy volunteers: Accepted

Summary

Feeding difficulties and airway related consequences contribute significantly to the infant mortality and morbidity. Some of these problems may be dependent on neural control and muscular function. Prematurity, congenital anomalies and perinatal depression represent three important conditions in infants, that may have feeding and airway difficulties.Development of motility of the foregut and the adaptation during normal and disease in developing infants is unclear.

Detailed description

With the aid of small clinical research funding from the NIDDK, in this proposal, we have developed methods to safely evaluate foregut motility in relation to breathing among high risk infants. We are using simultaneous esophageal motility studies, swallowing and respiratory measurements in this evaluation.

Conditions

• Infant, Premature, Diseases
• Congenital Abnormalities
• Perinatal Asphyxia

Timeline

• Start date: 2002-05-01
• Primary completion: 2005-04-01
• Completion: 2005-07-01
• First posted: 2003-06-06
• Last updated: 2017-10-06

Locations

1 site across 1 country: United States