Trials / Completed
CompletedNCT00055848
Genetic Study of Familial Factors in Patients With Colon Cancer
Familial Factors in the Development of Colon Cancer
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 600 (actual)
- Sponsor
- Alliance for Clinical Trials in Oncology · Academic / Other
- Sex
- All
- Age
- 70 Years
- Healthy volunteers
- Not accepted
Summary
RATIONALE: Genetic studies may help in understanding the genetic processes involved in the development of some types of cancer. PURPOSE: Clinical trial to study the cancer-related genes in patients who have colon cancer or adenomatous polyps.
Detailed description
OBJECTIVES: * Identify human colon neoplasia susceptibility genes in patients with colon cancer or adenomatous polyps. * Correlate the inheritance of novel susceptibility alleles for adenomatous polyposis of the colon with colon neoplasia in these patients. * Correlate colon neoplasia susceptibility with the presence of COX-2, sPLA2, and DNMT genes in these patients. * Identify a novel gene that governs increased susceptibility to colon adenoma and cancer in the genome of these patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | cytogenetic analysis | |
| GENETIC | gene mapping | |
| GENETIC | microarray analysis |
Timeline
- Start date
- 2001-12-01
- Primary completion
- 2010-10-01
- Completion
- 2010-10-01
- First posted
- 2003-03-07
- Last updated
- 2016-07-13
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00055848. Inclusion in this directory is not an endorsement.