Clinical Trials Directory

Trials / Completed

CompletedNCT00055471

A Phase IIa. Open-label, Multicenter, Dose-escalation Study to Assess the Tolerability and Pharmacokinetics of ZD4054 (Zibotentan) Given Orally Once Daily in Subjects With Metastatic Prostate Cancer

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
22 (actual)
Sponsor
AstraZeneca · Industry
Sex
Male
Age
18 Years
Healthy volunteers
Not accepted

Summary

The primary purpose of this study is to determine the safest dose of ZD4054 (Zibotentan)in men with prostate cancer

Conditions

Interventions

TypeNameDescription
DRUGZD4054 10 mg1 x 10 mg oral tablets once daily
DRUGZD4054 15 mg1 x 10 mg + 2 x 2.5 mg oral tablets once daily
DRUGZD4054 22.5 mg2 x 10 mg + 2 x 2.5 mg oral tablets once daily

Timeline

Start date
2003-06-01
Primary completion
2005-10-01
Completion
2005-10-01
First posted
2003-03-04
Last updated
2012-10-31
Results posted
2012-08-31

Locations

2 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00055471. Inclusion in this directory is not an endorsement.