Clinical Trials Directory

Trials / Completed

CompletedNCT00049842

Prevention of Disease Progress in Chronic Hepatitis C Patients With Liver Fibrosis (Study P02570AM2)(COMPLETED)

PEG-Intron(TM) Maintenance Therapy vs. an Untreated Control Group for Prevention of Progression of Fibrosis in Adult Subjects With Chronic Hepatitis C With Hepatic Fibrosis (METAVIR Fibrosis Score of F2 or F3), Who Failed Therapy With PEG-Intron Plus REBETOL(R) (in Protocol No. P02370)

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
540 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

The objective of the study is to evaluate the safety and efficacy of PEG-Intron versus no treatment for the prevention of fibrosis progression in adult participants with moderate to severe liver fibrosis secondary to chronic hepatitis C, who failed PEG-Intron plus Rebetol treatment in protocol P02370 (NCT00039871).

Conditions

Interventions

TypeNameDescription
BIOLOGICALpeginterferon alfa-2b (SCH 54031)0.5 µg/kg Weekly QW SC for 36 months

Timeline

Start date
2002-10-01
Primary completion
2009-10-01
Completion
2009-10-01
First posted
2002-11-15
Last updated
2017-04-04
Results posted
2011-01-20

Source: ClinicalTrials.gov record NCT00049842. Inclusion in this directory is not an endorsement.