Clinical Trials Directory

Trials / Completed

CompletedNCT00044356

Phase II Trial of Allovectin-7® for Metastatic Melanoma

A Phase II Study of High-Dose Allovectin-7® in Patients With Advanced Metastatic Melanoma

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
133 (actual)
Sponsor
Vical · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this clinical trial is to determine if Allovectin-7®, an experimental gene-based immunotherapy, can shrink melanoma tumors. The trial will also examine if this treatment can improve the time to disease progression.

Detailed description

Treatment - If you take part in this trial you will be treated for about 10 weeks. You will receive an injection of Allovectin-7® by needle, directly into one or more selected tumors once a week for the first six weeks. The injections may be given in a doctor's office. During a four-week observation period, your disease will be measured to see if the treatment is working. This will be done by general physical exams and scans (such as X-ray scans). Patients who show no sign of disease progression may be offered an option to repeat this treatment course.

Conditions

Interventions

TypeNameDescription
GENETICAllovectin-7®

Timeline

Start date
2001-02-01
Primary completion
2004-08-01
Completion
2004-09-01
First posted
2002-08-28
Last updated
2011-07-07

Locations

16 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00044356. Inclusion in this directory is not an endorsement.