Clinical Trials Directory

Trials / Completed

CompletedNCT00043966

Study of Lopinavir, Ritonavir, Tenofovir and Emtricitabine in HIV-Infected Antiretroviral Naïve Subjects

A Randomized, Open-Label Study of 800 Mg Lopinavir/200 Mg Ritonavir QD in Combination With Tenofovir and Emtricitabine Vs. 400 Mg Lopinavir /100 Mg Ritonavir BID in Combination With Tenofovir and Emtricitabine in HIV-Infected Antiretroviral Naïve Subjects

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
200 (planned)
Sponsor
Abbott · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to compare the safety, tolerability and antiviral activity between once-daily (QD) and twice-daily (BID) dosing of lopinavir/ritonavir and to further characterize the pharmacokinetics of once-daily dosing of lopinavir/ritonavir.

Conditions

Interventions

TypeNameDescription
DRUGLopinavir/ritonavir
DRUGTenofovir DF
DRUGEmtricitabine

Timeline

Start date
2002-07-01
First posted
2002-08-19
Last updated
2006-07-27

Locations

52 sites across 7 countries: United States, Australia, France, Germany, Singapore, Spain, United Kingdom

Source: ClinicalTrials.gov record NCT00043966. Inclusion in this directory is not an endorsement.