NCT00039507

Radiofrequency Ablation During Surgery in Treating Patients With Non-Small Cell Lung Cancer

Pilot Study: Radiofrequency Ablation Of Resectable Non-Small Cell Lung Cancer

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: —
• Sponsor: Fox Chase Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

RATIONALE: Radiofrequency ablation uses high-frequency electric current to kill tumor cells. Combining radiofrequency ablation with surgery may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining radiofrequency ablation with surgery in treating patients who have stage I or stage II non-small cell lung cancer.

Detailed description

OBJECTIVES: * Determine the acute effects of intraoperative radiofrequency tumor ablation (RFA) in patients with resectable non-small cell lung cancer. * Determine the treatment-related toxicity in patients treated with this therapy. * Determine the dimensions of the RFA lesion produced by the ablation procedure in these patients. OUTLINE: Patients undergo intraoperative radiofrequency tumor ablation over 10-15 minutes for each tumor immediately followed by tumor resection. PROJECTED ACCRUAL: A maximum of 20 patients will be accrued for this study.

Conditions

• Lung Cancer

Interventions

Type	Name	Description
PROCEDURE	conventional surgery
PROCEDURE	radiofrequency ablation

Timeline

• Start date: 2002-06-01
• Completion: 2004-02-01
• First posted: 2003-01-27
• Last updated: 2010-02-12

Locations

1 site across 1 country: United States