NCT00033813

KUL0401: An Open-label Pilot Study of Oxatomide in Steroid-Naive Duchenne Muscular Dystrophy

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 15 (planned)
• Sponsor: Cooperative International Neuromuscular Research Group · Network
• Sex: Male
• Age: 5 Years – 10 Years
• Healthy volunteers: Not accepted

Summary

This study will help to determine the safety and efficacy of the mast cell stabilizer Oxatomide as a treatment for Duchenne muscular dystrophy (DMD). Boys with DMD who are enrolled in this study will should not have taken steroids to treat DMD for at least twelve months, and should not have taken any nutritional supplements for at least three months. Subjects will complete a two screening visits within a one-week period, and if enrolled will then have their strength tested monthly for three months before beginning therapy with Oxatomide. Once Oxatomide therapy is started, participants will have their strength tested monthly for six months. Following the six month treatment period, participants will be given the option to remain on Oxatomide until the study is completed.

Conditions

• Muscular Dystrophy, Duchenne

Interventions

Type	Name	Description
DRUG	Oxatomide (tinset)

Timeline

• Start date: 2002-01-01
• Primary completion: 2006-12-01
• First posted: 2002-04-11
• Last updated: 2014-03-10

Locations

1 site across 1 country: United States