NCT00027430

Androgen Replacement Therapy in Women With Hypopituitarism

TheraDerm Administration in Women With Hypopituitarism

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

This is a study to determine whether testosterone replacement with TheraDerm can improve bone density, mood, sex drive, thinking, and distribution of body fat and muscle mass in women with hypopituitarism.

Detailed description

Patients will be randomized into 2 groups to receive testosterone replacement therapy or placebo. Group 1 will receive 2 testosterone patches and estrogen pills for 12 months. Group 2 will receive 2 placebo patches and estrogen pills for 12 months. Changes in bone density, bone metabolism markers, body composition, libido, and quality of life will be compared in the women receiving testosterone replacement therapy with that of the women receiving placebo. Completion date provided represents the completion date of the grant per OOPD records

Conditions

• Hypopituitarism

Interventions

Type	Name	Description
DRUG	TheraDerm

Timeline

• Start date: 2001-09-01
• Completion: 2004-12-01
• First posted: 2001-12-07
• Last updated: 2015-03-25

Locations

1 site across 1 country: United States