Trials / Completed
CompletedNCT00026013
Effects of St. John's Wort on the Effectiveness of Oral Contraceptives
Effects of Hypericum Perforatum on Effectiveness of Oral Contraceptives
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 25 (planned)
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH) · NIH
- Sex
- Female
- Age
- 18 Years – 40 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to evaluate the effects of a common herbal remedy, St. John's Wort, on the effectiveness of birth control pills. St. John's Wort has recently been shown to increase metabolism of some drugs. If it could increase metabolism of oral contraceptives as well, it may increase the risk of contraceptive failure and unintended pregnancy. Study participants will be evaluated for risk of ovulation on oral contraceptives before and during simultaneous therapy with St. John's Wort.
Detailed description
See Brief Summary
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | hypericum perforatum |
Timeline
- Start date
- 2002-01-01
- Completion
- 2004-01-01
- First posted
- 2001-11-06
- Last updated
- 2006-08-18
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00026013. Inclusion in this directory is not an endorsement.