Trials / Completed
CompletedNCT00018785
Living-Related Donor Bone Marrow Immunoregulation in Kidney Transplants
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- —
- Sponsor
- US Department of Veterans Affairs · Federal
- Sex
- All
- Age
- —
- Healthy volunteers
- Accepted
Summary
Diabetes and end-stage kidney, liver and heart disease are prominent health issues among veteran patients. Successful solid organ transplantation in the absence of chronic immunosuppressive therapy (specific acquired immunological tolerance) is a desirable therapeutic option. This project extends recent observations supporting the use of concommitant donor bone marrow cell infusion as a means of modulating the immune response in kidney transplantation, thereby allowing a substantial decrease or withdrawal of potentially toxic immunosuppressive drugs.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | donor bone marrow infusion |
Timeline
- Start date
- 1998-10-01
- Completion
- 2003-09-01
- First posted
- 2001-07-05
- Last updated
- 2009-01-21
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00018785. Inclusion in this directory is not an endorsement.