Trials / Completed
CompletedNCT00011141
Lactobacillus Plantarum as Therapy for NK-T Cell Deficiency
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- —
- Sponsor
- National Center for Research Resources (NCRR) · NIH
- Sex
- All
- Age
- 1 Year – 95 Years
- Healthy volunteers
- Not accepted
Summary
The etiology of immune-mediated diabetes mellitus (IMD) remains unclear. However, previous studies indicate that autoimmunity may be a result of dysfunction of natural killer T cells (NK-T cells). Newly diagnoses patients with IMD have been shown in our laboratory to have significantly lower NK-T cells than normal controls. Other studies have shown that oral administration of lactobacillus can boost NK-T cell activity in children with HIV without side effects. Our objective is to evaluate the effect of lactobacillus administration on NK-T cell activity in patients with IMD
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Oral lactobacillus administration |
Timeline
- First posted
- 2001-02-14
- Last updated
- 2005-06-24
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00011141. Inclusion in this directory is not an endorsement.