NCT00007254

Morphine Gel for Bedsores

Morphine-Infused Gel for Pressure Ulcer Analgesia

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 75 (planned)
• Sponsor: University of Kansas · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study tests the effectiveness of a morphine-containing gel for reducing pain caused by pressure ulcers, also known as bedsores or pressure sores. We will apply the gel containing morphine, or the gel alone, directly onto painful pressure ulcers and compare the results.

Detailed description

In this study, we will apply a morphine-containing gel (or placebo) directly onto painful pressure ulcers. We will take participants off of any opioid-containing medications upon entry into the study. This allows us to measure any morphine that may enter into the bloodstream from the topically applied gel. The purpose of this study is to examine the efficacy of the gel for pressure ulcer analgesia, as well as the systemic absorption of morphine from the topically applied gel. We will document the amount of pain medications taken by participants to determine whether the gel decreases the need for these drugs.

Conditions

• Decubitus Ulcer

Interventions

Type	Name	Description
DRUG	Pain relief for pressure ulcers

Timeline

• Start date: 2000-03-01
• Completion: 2003-02-01
• First posted: 2000-12-18
• Last updated: 2013-05-20

Locations

2 sites across 1 country: United States