Trials / Completed
CompletedNCT00005892
Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Myelodysplastic Syndrome and Acute Leukemia Related to Fanconi's Anemia
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- —
- Sponsor
- Fairview University Medical Center · Academic / Other
- Sex
- All
- Age
- 0 Years – 54 Years
- Healthy volunteers
- Not accepted
Summary
OBJECTIVES: I. Determine the effectiveness of moderate dose cyclophosphamide and radiotherapy in terms of improving survival and reducing the morbidity following allogeneic bone marrow transplantation in patients with myelodysplastic syndrome and acute leukemia related to Fanconi's anemia.
Detailed description
PROTOCOL OUTLINE: Patients receive cyclophosphamide IV over 1-2 hours on day -6 through -3 and total body radiotherapy on day -1. Patients undergo allogeneic bone marrow transplantation on day 0.
Conditions
- Fanconi's Anemia
- Myelodysplastic Syndromes
- Leukemia, Nonlymphocytic, Acute
- Leukemia, Lymphocytic, Acute
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | cyclophosphamide | |
| PROCEDURE | Allogeneic Bone Marrow Transplantation |
Timeline
- Start date
- 2000-03-01
- First posted
- 2000-06-05
- Last updated
- 2005-06-24
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00005892. Inclusion in this directory is not an endorsement.