Clinical Trials Directory

Trials / Completed

CompletedNCT00005864

Chloroquinoxaline Sulfonamide in Treating Patients With Stage IV Colorectal Cancer

A Phase II Study of Chloroquinoxaline Sulfonamide (CQS) in Colorectal Cancer Stage IV

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
Sponsor
Ohio State University Comprehensive Cancer Center · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of chloroquinoxaline sulfonamide in treating patients who have stage IV colorectal cancer.

Detailed description

OBJECTIVES: I. Assess the antitumor activity and toxicities of chloroquinoxaline sulfonamide in patients with stage IV colorectal cancer. OUTLINE: This is a multicenter study. Patients receive chloroquinoxaline sulfonamide IV over 1 hour weekly for 4 consecutive weeks. Treatment continues every 6 weeks in the absence of disease progression or unacceptable toxicity. Patients are followed for at least 30 days. PROJECTED ACCRUAL: A total of 16-25 patients will be accrued for this study within 8 months.

Conditions

Interventions

TypeNameDescription
DRUGchloroquinoxaline sulfonamide

Timeline

Start date
2000-04-01
Completion
2004-02-01
First posted
2004-02-25
Last updated
2013-01-31

Locations

4 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00005864. Inclusion in this directory is not an endorsement.