Trials / Completed
CompletedNCT00005837
Oxaliplatin in Treating Patients With Recurrent or Refractory Cervical Cancer
Phase II Evaluation of Oxaliplatin in Persistent or Recurrent Squamous Cell Carcinoma of the Cervix
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- —
- Sponsor
- Gynecologic Oncology Group · Network
- Sex
- Female
- Age
- —
- Healthy volunteers
- Not accepted
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of oxaliplatin in treating patients who have recurrent or refractory cervical cancer.
Detailed description
OBJECTIVES: I. Determine the antitumor activity of oxaliplatin by measuring response rate in patients with recurrent or refractory squamous cell carcinoma of the cervix who have failed on higher priority treatment protocols. II. Determine the nature and degree of toxicity of this drug in this patient population. OUTLINE: Patients receive oxaliplatin IV over 2 hours. Treatment continues every 21 days for a maximum of 9 courses in the absence of unacceptable toxicity or disease progression. Patients are followed every 3 months for 2 years and then every 6 months for 3 years. PROJECTED ACCRUAL: A total of 22-60 patients will be accrued for this study within 12-14 months.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | oxaliplatin |
Timeline
- Start date
- 2000-02-01
- Completion
- 2004-06-01
- First posted
- 2003-05-05
- Last updated
- 2013-06-21
Locations
72 sites across 2 countries: United States, Canada
Source: ClinicalTrials.gov record NCT00005837. Inclusion in this directory is not an endorsement.