Clinical Trials Directory

Trials / Completed

CompletedNCT00005809

Computerized Tomographic Colonography Compared With Standard Diagnostic Procedures in Detecting Colorectal Neoplasia

Computerized Tomographic Colonography: Performance Evaluation in a Multicenter Setting

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
Sponsor
American College of Radiology Imaging Network · Network
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

RATIONALE: New diagnostic procedures such as computed tomographic colonography may provide a less invasive method of identifying patients who have colorectal neoplasia. PURPOSE: Diagnostic study to compare the effectiveness of computerized tomographic colonography with that of standard diagnostic procedures in detecting colorectal neoplasia.

Detailed description

OBJECTIVES: I. Compare retrospectively the accuracy of computerized tomographic colonography (CTC) vs pathology and colonoscopy in the detection of clinically important colorectal neoplasia, defined as at least one proven lesion with a diameter measuring at least 1 cm. II. Compare the physician image display preferences and interpretation time across three viewing platforms for CTC images. OUTLINE: This is a retrospective, multicenter study. Radiologists evaluate each patient's optimal diagnostic computerized tomographic colonography (CTC) data. Patients' CTC findings are evaluated by a radiologist at a central facility using an imaging display software platform from General Electric, Vital Images, or the Mayo Clinic. CTC findings are compared with conventional colonoscopy findings and pathologic analysis. A comparison is made between physician image display preferences and interpretation time across three viewing platforms for CTC images. PROJECTED ACCRUAL: A total of 90 patients will be accrued for this study.

Conditions

Interventions

TypeNameDescription
PROCEDUREcomputed tomography
PROCEDUREdiagnostic colonoscopy

Timeline

Start date
2000-07-01
Primary completion
2000-10-01
Completion
2003-01-01
First posted
2004-04-19
Last updated
2013-02-04

Locations

11 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00005809. Inclusion in this directory is not an endorsement.