Clinical Trials Directory

Trials / Completed

CompletedNCT00005027

Rebeccamycin Analog in Treating Patients With Advanced Kidney Cancer

A Phase II Study of Rebeccamycin Analog in Renal Cell Cancer

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
Sponsor
Barbara Ann Karmanos Cancer Institute · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of rebeccamycin analog in treating patients who have advanced kidney cancer.

Detailed description

OBJECTIVES: * Determine the response rate of patients with advanced renal cell carcinoma when treated with rebeccamycin analogue. * Assess the quantitative and qualitative toxicities associated with this drug in this patient population. OUTLINE: Patients receive rebeccamycin analogue IV over 30-60 minutes daily for 5 days. Treatment continues every 21 days in the absence of disease progression or unacceptable toxicity. PROJECTED ACCRUAL: A total of 23-44 patients will be accrued for this study within 9-18 months.

Conditions

Interventions

TypeNameDescription
DRUGbecatecarin

Timeline

Start date
2000-06-01
Primary completion
2005-03-01
Completion
2005-03-01
First posted
2003-08-08
Last updated
2013-04-05

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00005027. Inclusion in this directory is not an endorsement.