Clinical Trials Directory

Trials / Completed

CompletedNCT00004814

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Copolymer 1 for Relapsing-Remitting Multiple Sclerosis

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
250 (planned)
Sponsor
National Center for Research Resources (NCRR) · NIH
Sex
All
Age
18 Years – 45 Years
Healthy volunteers
Not accepted

Summary

OBJECTIVES: I. Compare tolerance to and therapeutic impact of copolymer 1, a mixture of synthetic polypeptides, with placebo in patients with relapsing-remitting multiple sclerosis.

Detailed description

PROTOCOL OUTLINE: This is a randomized, double-blind study. Patients are stratified by participating institution. One group receives copolymer 1, a mixture of synthetic polypeptides composed of 4 amino acids, subcutaneously each day for 2 years. The other group receives an injection of placebo daily for 2 years.

Conditions

Interventions

TypeNameDescription
DRUGcopolymer 1

Timeline

Start date
1991-10-01
First posted
2000-02-25
Last updated
2005-06-24

Source: ClinicalTrials.gov record NCT00004814. Inclusion in this directory is not an endorsement.